The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2019

Filed:

May. 18, 2017
Applicants:

Chimerix, Inc., Durham, NC (US);

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

John Henry Bougher, III, Durham, NC (US);

Ramamurty V S Changalvala, Morrisville, NC (US);

John C. Drach, Ann Arbor, MI (US);

Ernest Randall Lanier, Jr., Chapel Hill, NC (US);

Andrew Louis McIver, Durham, NC (US);

Bradley David Robertson, Durham, NC (US);

Dean Wallace Selleseth, Cary, NC (US);

Phiroze Behram Sethna, Durham, NC (US);

Leroy Townsend, Ann Arbor, MI (US);

Roy W. Ware, Raleigh, NC (US);

Assignees:

Chimerix, Inc., Durham, NC (US);

The Regents of the University of Michigan, Ann Arbor, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 19/14 (2006.01); C07D 239/70 (2006.01); C07H 19/16 (2006.01); A61K 31/7052 (2006.01); A61K 31/706 (2006.01); A61K 31/7064 (2006.01);
U.S. Cl.
CPC ...
C07H 19/14 (2013.01); C07D 239/70 (2013.01); C07H 19/16 (2013.01); A61K 31/706 (2013.01); A61K 31/7052 (2013.01); A61K 31/7064 (2013.01);
Abstract

The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rand A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.


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