The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2019
Filed:
Mar. 25, 2016
Applicant:
Quimica Sintetica, S.a., Barcelona, ES;
Inventors:
Giuseppe Barreca, Montevecchia, IT;
Marcello Rasparini, Mol, BE;
Andrea Poggiali, Caronno Pertusella, IT;
Luca Carcone, Milan, IT;
Roberto Rocco Tufaro, Sozzago, IT;
Giovanni Marras, Galliate, IT;
Maurizio Taddei, Monteriggioni, IT;
Elena Cini, Gambassi Terme, IT;
Assignee:
QUIMICA SINTETICA, S.A., Barcelona, ES;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/10 (2006.01); C07H 1/00 (2006.01); C07H 19/06 (2006.01); C07H 1/02 (2006.01);
U.S. Cl.
CPC ...
C07H 19/10 (2013.01); C07H 1/00 (2013.01); C07H 1/02 (2013.01); C07H 19/06 (2013.01);
Abstract
Two processes are described for preparing, in different diastereomeric purity degrees, the compound (S)-isopropyl-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)-phosphoryl)amino) propanoate, having the formula given below, known as Sofosbuvir and used for the treatment of hepatitis C.