The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2019
Filed:
Aug. 19, 2016
Applicants:
Yang Ji Chemical Co., Ltd., Suwon-si, Gyeonggi-do, KR;
Han Wha Pharma Co., Ltd., Chuncheon-si, Gangwon-do, KR;
Inventors:
Chieyeon Chough, Suwon-si, KR;
Sunmin Lee, Hwaseong-si, KR;
Misuk Joung, Suwon-si, KR;
Hyun Uk Jeong, Suwon-si, KR;
Hong-sik Moon, Suwon-si, KR;
Assignees:
YANG JI CHEMICAL CO., LTD., Suwon-si, Gyeonggi-do, KR;
HAN WHA PHARMA CO., LTD., Chuncheon-si, Gangwon, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 487/04 (2006.01); C07D 403/12 (2006.01); A61K 31/506 (2006.01); A61P 29/00 (2006.01); A61P 37/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01); A61P 29/00 (2018.01); A61P 37/00 (2018.01); C07D 403/12 (2013.01);
Abstract
Provided are Janus kinase 1 selective inhibitors of Formula 1 or Formula 2: wherein R, R, and X are as described herein. Pharmaceutical uses thereof, for example, for the treatment of a disease associated with a Janus kinase, are also provided.