The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2019
Filed:
Nov. 15, 2016
Fundación Para LA Investigación Médica Aplicada, Pamplona, ES;
Xabier Aguirre Ena, Pamplona, ES;
Julen Oyarzabal Santamarina, Pamplona, ES;
Felipe Prósper Cardoso, Pamplona, ES;
Maria Obdulia Rabal Gracia, Pamplona, ES;
Edurne San José Enériz, Pamplona, ES;
Juan Antonio Sánchez Arias, Pamplona, ES;
FUNDACIÓN PARA LA INVESTIGACIÓN MÉDICA APLICADA, Pamplona, ES;
Abstract
It relates to the compounds of formula (I), or their pharmaceutically or veterinary acceptable salts, or their stereoisomers or mixtures thereof, wherein A, R, R, and Rare as defined herein, which are inhibitors of one or more DNMTs selected from the group consisting of DNMT1, DNMT3A and DNMT3B. It also relates to pharmaceutical or veterinary compositions containing them, and to their use in medicine, in particular in the treatment and/or prevention of cancer, fibrosis and/or immunomodulation.