The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2019

Filed:

Sep. 28, 2017
Applicant:

Nektar Therapeutics, San Francisco, CA (US);

Inventors:

Neel K. Anand, San Mateo, CA (US);

Franco J. Duarte, Walnut Creek, CA (US);

Wen Zhang, San Ramon, CA (US);

Zhongxu Ren, Foster City, CA (US);

Assignee:

Nektar Therapeutics, San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 409/12 (2006.01); C07D 333/48 (2006.01); C07D 241/04 (2006.01); C07D 207/12 (2006.01); C07D 207/14 (2006.01); C07D 213/56 (2006.01); C07D 213/61 (2006.01); C07C 233/40 (2006.01); C07D 205/04 (2006.01); C07D 295/125 (2006.01); C07C 233/05 (2006.01); C07D 207/09 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 409/12 (2013.01); C07C 233/05 (2013.01); C07C 233/40 (2013.01); C07D 205/04 (2013.01); C07D 207/09 (2013.01); C07D 207/12 (2013.01); C07D 207/14 (2013.01); C07D 213/56 (2013.01); C07D 213/61 (2013.01); C07D 241/04 (2013.01); C07D 295/125 (2013.01); C07D 333/48 (2013.01); C07D 401/12 (2013.01);
Abstract

Provided are compounds of Formula I: and pharmaceutically acceptable salts and solvates thereof, wherein R, R, R, R, R, and Rare as described herein. The compounds of Formula I are agonists of the kappa opioid receptor and relate to and/or have application(s) in (among others) the fields of drug discovery, pharmacotherapy, physiology, organic chemistry and polymer chemistry.


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