The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2019
Filed:
May. 11, 2016
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventors:
Philip Stewart Low, West Lafayette, IN (US);
Venkatesh Chelvam, West Lafayette, IN (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/35 (2006.01); A61K 38/08 (2019.01); A61K 45/06 (2006.01); A61K 47/54 (2017.01); A61K 47/55 (2017.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); G01N 33/84 (2006.01); G01N 33/533 (2006.01);
U.S. Cl.
CPC ...
A61K 47/551 (2017.08); A61K 31/35 (2013.01); A61K 38/08 (2013.01); A61K 45/06 (2013.01); A61K 47/54 (2017.08); A61P 29/00 (2018.01); A61P 35/00 (2018.01); G01N 33/84 (2013.01); G01N 33/533 (2013.01);
Abstract
The invention described herein pertains to ligand-ionophore conjugates, that may also comprise a linked therapeutic agent or imaging agent, and pharmaceutical compositions containing the conjugates. Also described are methods of using the conjugates for increasing the endosomal accumulation and escape of a therapeutic agent, or an imaging agent.