The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2019

Filed:

Jun. 02, 2016
Applicant:

Green Cross Holdings Corporation, Youngin-si, Gyeonggi-do, KR;

Inventors:

Yong Won Shin, Suwon-si, KR;

Dong Il Park, Cheongju-si, KR;

Chung Mo Ahn, Cheongju-si, KR;

Jong Kyung Kim, Cheongju-si, KR;

Dong Hwee Lee, Cheongju-si, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); C07H 21/04 (2006.01); A61K 38/00 (2006.01); C07K 16/08 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); B01D 15/36 (2006.01); C07K 16/10 (2006.01); C07K 1/18 (2006.01); C07K 1/34 (2006.01); A61P 43/00 (2006.01); A61P 1/00 (2006.01); A61K 39/29 (2006.01); A61K 39/42 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39525 (2013.01); A61K 39/29 (2013.01); A61K 39/395 (2013.01); A61K 39/42 (2013.01); A61P 1/00 (2018.01); A61P 43/00 (2018.01); B01D 15/36 (2013.01); C07K 1/18 (2013.01); C07K 1/34 (2013.01); C07K 16/10 (2013.01); A61K 2039/505 (2013.01);
Abstract

The present invention relates to a preparation method of a human plasma-derived hepatitis B immunoglobulin preparation. More specifically, the present invention relates to a preparation method of a human plasma-derived hepatitis B immunoglobulin preparation characterized in that plasma protein fraction II (fraction II) containing human hepatitis B immunoglobulin is dialysis concentrated and then thrombus-producing materials and impurities formed during processes are removed by anion exchange resin and cation exchange resin purification techniques. By using the preparation method of the human plasma-derived hepatitis B immunoglobulin preparation according to the present invention, the efficiency of removing impurities and thrombus-producing materials is increased and a polymer content is maintained, whereby it is possible to produce human hepatitis B immunoglobulin with stable and improved quality.


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