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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10406185 B1

PDFFull Text
Date of Patent:
Sep. 10, 2019

Filed:

Dec. 28, 2017

Cancer therapy with a parvovirus combined with a bcl-2 inhibitor

Applicants:

Deutsches Krebsforschungszentrum, Heidelberg, DE;

Ruprecht-karls-universität Heidelberg, Heidelberg, DE;

Inventors:

Antonio Marchini, Heidelberg, DE;

Junwei Li, Eppelheim, DE;

Lea Schroeder, Heidelberg, DE;

Jean Rommelaere, Heidelberg, DE;

Karsten Geletneky, Heidelberg, DE;

Assignees:

DEUTSCHES KREBSFORSCHUNGSZENTRUM, Heidelberg, DE;

RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG, Heidelberg, DE;

Attorneys:

Duane Morris LLP

Thomas J. Kowalski

Deborah L. Lu

Primary Examiner:

Bao Q Li

Int. Cl.
CPC ...
A61K 35/768 (2015.01); A61K 45/06 (2006.01); A61K 31/495 (2006.01); A61K 31/5377 (2006.01); A61K 31/63 (2006.01); A61K 31/635 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61K 31/495 (2013.01); A61K 31/5377 (2013.01); A61K 31/63 (2013.01); A61K 31/635 (2013.01); A61K 45/06 (2013.01); C12N 2750/14332 (2013.01);
Abstract

Described is a pharmaceutical composition comprising (a) a parvovirus and (b) an Bcl-2 inhibitor and the use of said composition for treatment of cancer, e.g., a solid tumor. Preferred inhibitors are the BH3 mimetics ABT-737 and ABT-199.

Find Patent Forward Citations

Marchini, Antonio. (2019). Cancer therapy with a parvovirus combined with a bcl-2 inhibitor (U.S. Patent No. 10406185). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10406185

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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