The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2019

Filed:

Mar. 09, 2016
Applicants:

Rhodes Technologies, Coventry, RI (US);

C. Frederick M. Huntley, East Greenwich, RI (US);

Erik Wayne Kataisto, Coventry, RI (US);

Helge Alfred Reisch, Westerly, RI (US);

Archana Sharma, East Greenwich, RI (US);

Inventors:

C. Frederick M. Huntley, East Greenwich, RI (US);

Erik Wayne Kataisto, Coventry, RI (US);

Helge Alfred Reisch, Westerly, RI (US);

Archana Sharma, East Greenwich, RI (US);

Assignee:

RHODES TECHNOLOGIES, Coventry, RI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/485 (2006.01); C07D 489/12 (2006.01); A61P 25/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/485 (2013.01); A61P 25/04 (2018.01); C07D 489/12 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present disclosure provides acetate salts of buprenorphine, and its anhydrates, solvates, hydrates, and crystalline forms thereof, where the acetate salts of buprenorphine are essentially free of impurities. The disclosure further provides method of preparing the acetate salts, buprenorphine free base prepared from the acetate salts, other salts prepared from the free base, and pharmaceutical compositions thereof essentially free of impurities.


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