The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2019

Filed:

Mar. 31, 2017
Applicant:

Lipoxen Technologies Limited, London, GB;

Inventors:

Dmitry Genkin, St. Petersburg, RU;

Kirill Surkov, St. Petersburg, RU;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/473 (2006.01); A61K 31/135 (2006.01); A61K 31/138 (2006.01); A61K 31/40 (2006.01); A61K 31/565 (2006.01); A61K 31/57 (2006.01); A61K 31/58 (2006.01);
U.S. Cl.
CPC ...
A61K 31/473 (2013.01); A61K 31/135 (2013.01); A61K 31/138 (2013.01); A61K 31/40 (2013.01); A61K 31/565 (2013.01); A61K 31/57 (2013.01); A61K 31/58 (2013.01);
Abstract

The invention provides a method for treatment of primary progesterone receptor-negative (PR−) endometrial cancer comprising administering (i) cridanimod or a salt or an ester thereof and (ii) a progesterone receptor (PR) agonist. The invention further provides a method for treatment of a primary estrogen receptor-negative (ER−) breast cancer, comprising administering (i) cridanimod or a salt or an ester thereof and (ii) a selective estrogen receptor modulator (SERM) or a selective estrogen receptor down-regulator (SERD). Also provided are compositions related to the above methods.


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