The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2019

Filed:

Jul. 12, 2016
Applicants:

Seoul National University R & Db Foundation, Seoul, KR;

Korea Research Institute of Standards and Science, Daejeon, KR;

Inventors:

Jeong Hun Kim, Seoul, KR;

Dong Hyun Jo, Seoul, KR;

Tae Geol Lee, Daejeon, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/51 (2006.01); A61K 47/42 (2017.01); A61P 27/02 (2006.01); B82Y 5/00 (2011.01); G01N 33/15 (2006.01); G01N 33/68 (2006.01); A61K 9/50 (2006.01); A61K 9/16 (2006.01); A61K 33/00 (2006.01); A61K 33/24 (2019.01); G01N 33/50 (2006.01); A61K 47/69 (2017.01); A61P 27/00 (2006.01); A61K 9/00 (2006.01); A61K 38/38 (2006.01); B82Y 30/00 (2011.01);
U.S. Cl.
CPC ...
A61K 9/51 (2013.01); A61K 9/0048 (2013.01); A61K 9/146 (2013.01); A61K 9/16 (2013.01); A61K 9/5052 (2013.01); A61K 9/5169 (2013.01); A61K 33/00 (2013.01); A61K 33/24 (2013.01); A61K 38/385 (2013.01); A61K 47/42 (2013.01); A61K 47/6923 (2017.08); A61K 47/6925 (2017.08); A61P 27/00 (2018.01); A61P 27/02 (2018.01); G01N 33/15 (2013.01); G01N 33/50 (2013.01); G01N 33/68 (2013.01); B82Y 5/00 (2013.01); B82Y 30/00 (2013.01);
Abstract

Provided is a nanoparticle-vitreous body-based protein complex, and more particularly, to a composition for inhibiting angiogenesis which includes the complex as an active ingredient, and a composition for preventing or treating an angiogenesis-related disease or a retinal disease. When the nanoparticle-vitreous body-based protein complex according to the subject matter is locally injected into the vitreous body, the complex exhibits significantly excellent binding strength with a vascular endothelial growth factor and thus can inhibit angiogenesis, thus being easily used to prepare a therapeutic agent for preventing, alleviating, or treating retinal and choroidal angiogenesis-related diseases.


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