The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2019

Filed:

Sep. 22, 2016
Applicant:

Boston Scientific Scimed, Inc., Maple Grove, MN (US);

Inventors:

Crystal Marie Anderson-Cunanan, San Jose, CA (US);

Katherine Cora Fazackerley, San Mateo, CA (US);

Michael Eppihimer, Franklin, MA (US);

Shannon Smith Kenwood, Winthrop, MA (US);

Natalia P. Sushkova, Chestnut Hill, MA (US);

Karen Suzanne Lavery, Franklin, MA (US);

Assignee:

Boston Scientific Scimed, Inc., Maple Grove, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/24 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/50 (2006.01); C12N 5/077 (2010.01); C12M 3/00 (2006.01);
U.S. Cl.
CPC ...
A61F 2/2415 (2013.01); A61F 2/2412 (2013.01); A61F 2/2418 (2013.01); A61L 27/3687 (2013.01); A61L 27/3804 (2013.01); A61L 27/3826 (2013.01); A61L 27/3873 (2013.01); A61L 27/3886 (2013.01); A61L 27/3895 (2013.01); A61L 27/507 (2013.01); C12N 5/0656 (2013.01); C12N 5/0661 (2013.01); A61L 2430/20 (2013.01); C12M 21/08 (2013.01); C12N 2502/1347 (2013.01); C12N 2527/00 (2013.01); C12N 2537/10 (2013.01);
Abstract

A prosthetic heart valve provided herein can include a cultured cell tissue leaflet. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member. The cultured cell tissue can be obtained by culturing fibroblast cells, smooth muscle cells, or a combination thereof to form a sheet of cultured cells and chemically cross-linking the fibroblast cells while under tension. In some cases, the cultured cell tissue can be radially tensioned. In some cases, the cultured cell tissue can be bi-axially tensioned.


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