The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
Feb. 13, 2015
Siemens Healthcare Gmbh, Erlangen, DE;
Institut National DE Recherche En Informatique ET En Automatique, Le Chesnay, FR;
Chloe Audigier, Valbonnes, FR;
Tommaso Mansi, Plainsboro, NJ (US);
Saikiran Rapaka, Pennington, NJ (US);
Ali Kamen, Skillman, NJ (US);
Viorel Mihalef, North Brunswick, NJ (US);
Herve Delingette, La Colle sur Loup, FR;
Nicholas Ayache, Nice, FR;
Dorin Comaniciu, Princeton Junction, NJ (US);
Siemens Healthcare GmbH, Erlangen, DE;
Institut National de Recherche en Informatique et en Automatique, Le Chesnay, FR;
Abstract
A method and system for personalized computation of tissue ablation extent based on medical images of a patient is disclosed. A patient-specific anatomical model of the liver and liver vessels is estimated from medical image data of a patient. Blood flow in the liver and liver vessels is simulated. An ablation simulation is performed that uses a bio-heat model to simulate heat diffusion due to an ablation based on the simulated blood flow and a cellular necrosis model to simulate cellular necrosis in the liver based on the simulated heat diffusion. Personalized tissue parameters of the bio-heat model and the cellular necrosis model are estimated based on observed results of a preliminary ablation procedure. Planning of the ablation procedure is then performed using the personalized bio-heat equation and the cellular necrosis model. The model can be subsequently refined as more ablation observations are obtained.