The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

Dec. 15, 2017
Applicants:

Screen Holdings Co., Ltd., Kyoto-shi, Kyoto, JP;

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Joseph Russell Landry, Stanford, CA (US);

Ryosuke Itoh, Stanford, CA (US);

Michael J. Mandella, Palo Alto, CA (US);

Olav Solgaard, Stanford, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G02B 21/00 (2006.01); G01N 21/64 (2006.01); G02B 21/36 (2006.01);
U.S. Cl.
CPC ...
G02B 21/0088 (2013.01); G01N 21/6458 (2013.01); G02B 21/0032 (2013.01); G02B 21/0076 (2013.01); G02B 21/365 (2013.01); G02B 21/367 (2013.01); G01N 2201/0675 (2013.01);
Abstract

A system, including a structured illumination stage to provide a spatially modulated imaging field is provided. The system further includes a spatial frequency modulation stage to adjust the frequency of the spatially modulated imaging field, a sample interface stage to direct the spatially modulated imaging field to a sample, and a sensor configured to receive a plurality of fluorescence emission signals from the sample. The system also includes a processor configured to reduce a sample scattering signal and to provide a fluorescence emission signal from a portion of the sample including the spatially modulated imaging field. A method for using the above system to form an image of the sample is also provided.


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