The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

Oct. 27, 2015
Applicant:

True Health Ip Llc, Frisco, TX (US);

Inventors:

Philip Guadagno, Vashon Island, WA (US);

Erin Grace Summers Bellin, Sandston, VA (US);

Daniel M. Hoefner, Ashland, VA (US);

Mohmed Ashmaig, Glen Allen, VA (US);

Assignee:

True Health IP LLC, Frisco, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/92 (2006.01); A61K 31/4535 (2006.01); A61K 31/235 (2006.01); A61K 31/455 (2006.01); A61K 31/566 (2006.01); A61K 31/397 (2006.01); G16H 50/30 (2018.01); G06F 19/00 (2018.01);
U.S. Cl.
CPC ...
G01N 33/92 (2013.01); A61K 31/235 (2013.01); A61K 31/397 (2013.01); A61K 31/455 (2013.01); A61K 31/4535 (2013.01); A61K 31/566 (2013.01); G06F 19/00 (2013.01); G16H 50/30 (2018.01); G01N 2333/775 (2013.01); G01N 2800/044 (2013.01); G01N 2800/32 (2013.01); Y02A 90/26 (2018.01);
Abstract

The application describes methods for determining the particle number and/or molar mass of lipoprotein(a) subform(s) in a biological sample using enzyme linked immunosorbent assay (ELISA). The methods described herein significantly improve lipoprotein ELISA methods and devices capable of quantifying particle numbers and population mass of Lp(a) particles. This technology offers a method for the efficient and cost-effective measurement of specific Lp(a) in a rapid, low-cost format, rather than limited measurement of Lp(a) concentration in patient tissues. The ability to measure the particle number and/or molar mass of lipoprotein(a) subform(s) in a biological sample also provides a useful diagnostic tool for assessing cardiovascular risk in a subject.


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