The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

Mar. 19, 2015
Applicant:

Novozymes, Inc., Davis, CA (US);

Inventors:

Suchindra Maiyuran, Gold River, CA (US);

Abigail Jang, Antelope, CA (US);

Kimberly Brown, Elk Grove, CA (US);

Sandra Merino, West Sacramento, CA (US);

Jeffrey Shasky, Davis, CA (US);

Eric Abbate, Vacaville, CA (US);

Assignee:

Novozymes, Inc., Davis, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/58 (2006.01); C12P 21/00 (2006.01); C12N 15/80 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); C12N 9/58 (2013.01); C12N 15/80 (2013.01); C12P 21/02 (2013.01);
Abstract

The present invention relates to mutants of a parentstrain, comprising a polynucleotide encoding a polypeptide and one or more (several) genes selected from the group consisting of a first subtilisin-like serine protease gene, a first aspartic protease gene, a trypsin-like serine protease gene, a second subtilisin-like serine protease gene, and a second aspartic protease gene, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of a first subtilisin-like serine protease, a first aspartic protease, a trypsin-like serine protease, a second subtilisin-like serine protease, and a second aspartic protease, respectively, compared to the parentstrain when cultivated under identical conditions. The present invention also relates to methods of producing a polypeptide in such mutants and methods for producing such mutants.


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