The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

Oct. 17, 2013
Applicants:

Tokushima University, Tokushima-shi, Tokushima, JP;

Meiji Pharmaceutical University, Kiyose-shi, Tokyo, JP;

Inventors:

Koji Ito, Tokushima, JP;

Hitoshi Sakuraba, Kiyose, JP;

Daisuke Tsuji, Tokushima, JP;

Assignees:

TOKUSHIMA UNIVERSITY, Tokushima-Shi, Tokushima, JP;

MEJI PHARMACEUTICAL UNIVERSITY, Kiyose-Shi, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/24 (2006.01); A61K 38/47 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2402 (2013.01); A61K 38/47 (2013.01); C12Y 302/01052 (2013.01); A61K 38/00 (2013.01);
Abstract

Provided is a modified β-subunit of human β-hexosaminidase which has the activity derived from the α-subunit of wild-type human β-hexosaminidase and has the resistance to protease. A protein comprising an amino acid sequence having substitutions of the 312th to the 318th amino acids with glycine, serine, glutamic acid, proline, serine, glycine and threonine in order, respectively, in an amino acid sequence of a β-subunit of wild-type human β-hexosaminidase.


Find Patent Forward Citations

Ito, Koji. (2019). High functional enzyme having modified substrate specificity of human β-hexosaminidase b and exhibiting protease resistance (U.S. Patent No. 10400226). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10400226

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…