The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

Dec. 18, 2014
Applicant:

Fenwal, Inc., Lake Zurich, IL (US);

Inventors:

Christopher J. Wegener, Libertyville, IL (US);

Daniel R. Boggs, Libertyville, IL (US);

Bret M. Olson, Evanston, IL (US);

Assignee:

Fenwal, Inc., Lake Zurich, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/02 (2006.01); A61M 1/26 (2006.01); A61M 1/34 (2006.01); A61M 1/36 (2006.01); B01D 61/00 (2006.01); B01D 61/18 (2006.01); B01D 63/06 (2006.01); B01D 63/16 (2006.01); B01D 71/50 (2006.01); C12N 5/078 (2010.01); B01D 71/40 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0641 (2013.01); A61M 1/0209 (2013.01); A61M 1/0218 (2014.02); A61M 1/0236 (2014.02); A61M 1/265 (2014.02); A61M 1/34 (2013.01); B01D 61/00 (2013.01); B01D 61/18 (2013.01); B01D 63/062 (2013.01); B01D 63/065 (2013.01); B01D 63/16 (2013.01); B01D 71/50 (2013.01); A61M 1/3692 (2014.02); A61M 2202/0429 (2013.01); A61M 2202/0439 (2013.01); B01D 71/40 (2013.01); B01D 2311/04 (2013.01); B01D 2315/02 (2013.01);
Abstract

Systems and methods for the washing of biological fluid/biological cells are disclosed. The method provides for the automated dilution of the cell feed during the cell washing procedure using a separator in which the separator has a predetermined maximum output concentration for the biological cells that are being washed. The method further includes determining the concentration ratio of the biological cells to be washed in the washing procedure and determining a maximum input concentration as a function of the maximum output concentration and the concentration ratio. Wash solution is then added to dilute said biological cells so that the maximum input concentration of the diluted biological cells entering the separator is not exceeded.


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