The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

Dec. 07, 2016
Applicant:

Pieris Pharmaceuticals Gmbh, Freising-Weihenstephan, DE;

Inventors:

Gabriele Matschiner, Munich, DE;

Christine Rothe, Dauchau, DE;

Alexander Wiedenmann, Ulm, DE;

Rachida Siham Bel Aiba, Munich, DE;

Marlon Hinner, Munich, DE;

Andrea Allersdorfer, Wolnzach, DE;

Bradley Lunde, Munich, DE;

Kazufumi Kubota, Tokyo, JP;

Mitsuhiro Makino, Tokyo, JP;

Sakiko Takahashi, Tokyo, JP;

Ryuji Hashimoto, Tokyo, JP;

Tohru Takahashi, Tokyo, JP;

Mamoru Otoyo, Tokyo, JP;

Assignee:

PIERIS PHARMACEUTICALS GMBH, Freising-Weihenstephan, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/31 (2013.01);
Abstract

The present disclosure provides hNGAL muteins that bind CGRP and can be used in various application including pharmaceutical applications, for example, migraine. The present disclosure also concerns methods of making one or more muteins described herein as well as compositions and combinations comprising one or more of such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and to methods for generation of such muteins and nucleic acid molecules. In addition, the application discloses therapeutic and/or diagnostic uses of these muteins as well as compositions and combinations comprising one or more of such muteins.


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