The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
Apr. 15, 2014
Applicant:
Asahi Kasei Medical Co., Ltd., Tokyo, JP;
Inventors:
Hiroki Taniguchi, Tokyo, JP;
Masako Goto, Tokyo, JP;
Ichiro Koguma, Tokyo, JP;
Yoshiro Yokoyama, Tokyo, JP;
Assignee:
ASAHI KASEI MEDICAL CO., LTD., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/36 (2006.01); B01D 15/38 (2006.01); B01J 20/26 (2006.01); B01J 39/05 (2017.01); B01J 39/17 (2017.01); B01J 39/20 (2006.01); B01J 38/26 (2006.01); B01J 49/06 (2017.01); C07K 1/18 (2006.01); C07K 1/22 (2006.01); C07K 16/00 (2006.01); G01N 30/30 (2006.01); G01N 30/54 (2006.01); G01N 30/96 (2006.01); G01N 30/88 (2006.01); B01J 39/26 (2006.01); B01D 15/32 (2006.01); B01D 15/42 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); B01D 15/361 (2013.01); B01D 15/362 (2013.01); B01D 15/38 (2013.01); B01D 15/3804 (2013.01); B01D 15/3809 (2013.01); B01D 15/3876 (2013.01); B01J 20/26 (2013.01); B01J 20/264 (2013.01); B01J 20/267 (2013.01); B01J 39/05 (2017.01); B01J 39/17 (2017.01); B01J 39/20 (2013.01); B01J 39/26 (2013.01); B01J 49/06 (2017.01); C07K 1/18 (2013.01); C07K 16/00 (2013.01); G01N 30/30 (2013.01); G01N 30/54 (2013.01); G01N 30/96 (2013.01); B01D 15/32 (2013.01); B01D 15/327 (2013.01); B01D 15/424 (2013.01); G01N 2030/8813 (2013.01);
Abstract
A method for purifying a biologically active substance from a solution mixture containing impurities and the biologically active substance, in which an ion exchange chromatography carrier comprising a matrix and a copolymer containing at least N-isopropylacrylamide as a monomer unit and immobilized to a surface of the matrix is used, and the solution mixture is allowed to flow through a container storing the carrier at a uniform temperature, thereby recovering the biologically active substance.