The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
Jul. 24, 2017
Innovative Pharmacology Research Ooo (Iphar), Tomsk, RU;
Olga Anatolyevna Luzina, Novosibirsk, RU;
Alexandra Leonidovna Zakharenko, Novosibirsk, RU;
Dmitry Nikolaevich Sokolov, Novosibirskaya oblast, r.p.Koltsovo, RU;
Nariman Faridovich Salakhutdinov, Novosibirsk, RU;
Olga Ivanovna Lavrik, Novosibirsk, RU;
Veniamin Abramovich Khazanov, Tomsk, RU;
INNOVATIVE PHARMACOLOGY RESEARCH OOO (IPHAR), Tomsk, RU;
Abstract
The present invention relates to the field of molecular biology, biochemistry and biotechnology, namely, to compound 2-acetyl-6-(2-(2-(4-bromobenzylidene)hydrazinyl) thiazole-4-yl)-3,7,9-trihydroxy-8,9b-dimethyldibenzo[b,d]furan-1(9bh)-one, which is a hydrazine-thiazole derivative of usnic acid of formula I and which is able to inhibit the action of human tyrosyl-DNA-phosphodiesterase 1 enzyme. Technical result: increase in inhibitory action towards human tyrosyl-DNA-phosphodiesterase 1 enzyme (Tdp1) and increase in the number of inhibitors of this enzyme. 1 independent claim, 2 figures, 3 examples.