The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

Oct. 05, 2016
Applicants:

Mitobridge, Inc., Cambridge, MA (US);

The Salk Institute for Biological Studies, La Jolla, CA (US);

Inventors:

Michael Downes, La Jolla, CA (US);

Ronald M. Evans, La Jolla, CA (US);

Arthur Kluge, Lincoln, MA (US);

Bharat Lagu, Acton, MA (US);

Masanori Miura, Tsukuba, JP;

Sunil Kumar Panigrahi, Hyderabad, IN;

Michael Patane, Andover, MA (US);

Susanta Samajdar, Hyderabad, IN;

Ramesh Senaiar, Hyderabad, IN;

Taisuke Takahashi, Tsukuba, JP;

Assignees:

Mitobridge, Inc., Cambridge, MA (US);

The Salk Institute for Biological Studies, La Jolla, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/64 (2006.01); C07D 401/04 (2006.01); C07D 405/10 (2006.01); A61P 21/00 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61P 21/00 (2018.01); A61P 25/00 (2018.01); C07D 233/64 (2013.01); C07D 405/10 (2013.01);
Abstract

Provided herein are compounds I, II or III and compositions useful in increasing PPAR8 activity. The compounds and compositions provided herein are useful for the treatment of PPAR8 related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).


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