The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
Feb. 10, 2016
Applicant:
Vanderbilt University, Nashville, TN (US);
Inventors:
P. Jeffrey Conn, Nashville, TN (US);
Craig W. Lindsley, Brentwood, NC (US);
Kyle A. Emmitte, Aledo, TX (US);
Julie L. Engers, Brentwood, TN (US);
Katrina A. Bollinger, Murfreesboro, TN (US);
Megan M. Breiner, Memphis, TN (US);
Assignee:
Vanderbilt University, Nashville, TN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/04 (2006.01); C07D 213/69 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); A61K 31/444 (2006.01); A61K 31/435 (2006.01); C07D 239/60 (2006.01); C07D 237/16 (2006.01); C07D 239/52 (2006.01);
U.S. Cl.
CPC ...
C07D 239/60 (2013.01); C07D 213/04 (2013.01); C07D 213/69 (2013.01); C07D 237/16 (2013.01); C07D 239/52 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01);
Abstract
Described are negative allosteric modulators of metabotropic glutamate receptor 3 (mGlu3), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating depression, cognitive disorders, schizophrenia, Alzheimer's disease, or cancer in a subject.