The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
Dec. 29, 2017
Northwestern University, Evanston, IL (US);
Chad A. Mirkin, Wilmette, IL (US);
Caroline H. Ko, Chicago, IL (US);
David A. Giljohann, Chicago, IL (US);
Janina Luciano, Champaign, IL (US);
Samuel A. Jensen, Bloomington, MN (US);
Alexander Stegh, Chicago, IL (US);
NORTHWESTERN UNIVERITY, Evanston, IL (US);
Abstract
Polyvalent nanoconjugates address the critical challenges in therapeutic use. The single-entity, targeted therapeutic is able to cross the blood-brain barrier (BBB) and is thus effective in the treatment of central nervous system (CNS) disorders. Further, despite the tremendously high cellular uptake of nanoconjugates, they exhibit no toxicity in the cell types tested thus far. This property is critical for therapeutic agent delivery applications for reducing off-target effects.