The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

Oct. 20, 2017
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Ivar M. McDonald, East Haddam, CT (US);

Prasanna Sivaprakasam, Lawrenceville, NJ (US);

Christiana I. Iwuagwu, Hamden, CT (US);

Kevin M. Peese, Haddam, CT (US);

Heng Cheng, Fremont, CA (US);

Naidu S. Chowdari, Sunnyvale, CA (US);

Sanjeev Gangwar, Foster City, CA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 47/68 (2017.01); C07D 519/00 (2006.01); C07F 7/08 (2006.01); C07K 5/062 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6803 (2017.08); C07D 471/04 (2013.01); C07D 519/00 (2013.01); C07F 7/0814 (2013.01); C07K 5/06026 (2013.01);
Abstract

A compound capable of inhibiting cell proliferation, having a structure according to formula (I) wherein the variables in formula (I) are as defined in the specification. Such compounds are useful as anti-cancer agents, especially in antibody-drug conjugates.


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