The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
May. 23, 2018
Novo Nordisk A/s, Bagsvaerd, DK;
Xiang Gao, Beijing, CN;
Xujia Zhang, Beijing, CN;
Hongtao Guan, Shanghai, CN;
Henning Thoegersen, Farum, DK;
Kristian Sass-Oerum, Copenhagen V, DK;
Lars Fogh Iversen, Holte, DK;
Per Noergaard, Humlebaek, DK;
Sebastian Beck Joergensen, Virum, DK;
Kristian Tage Hansen, Slangerup, DK;
Yi Wang, Beijing, CN;
Kilian Waldemar Conde Frieboes, Maaloev, DK;
Birgit Wieczorek, Copenhagen N, DK;
Novo Nordisk A/S, Bagsvaerd, DK;
Abstract
The invention relates to MIC-1 compounds. More specifically it relates to compounds comprising a MIC-1 polypeptide with an N-terminal amino acid extension and a protractor wherein the amino acid extension comprises 3 to 36 amino acid residues and where the MIC-1 polypeptide and the N-terminal amino acid extension together have a calculated pI lower than 6.5. The compounds of the invention have MIC-1 activity. The invention also relates to pharmaceutical compositions comprising such compounds and pharmaceutically acceptable excipients, as well as the medical use of the compounds.