The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

Mar. 21, 2016
Applicant:

Salupont Consulting Ltd., Sandy Bedfordshire, GB;

Inventors:

Daryl Rees, Sandy, GB;

Antonia Orsi, Sandy, GB;

Assignee:

Salupont Consulting Ltd., Sandy Bedfordshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 2/00 (2006.01); A61K 41/00 (2006.01); A61K 38/05 (2006.01); A61K 31/198 (2006.01); A61P 1/00 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0009 (2013.01); A61K 31/198 (2013.01); A61K 38/05 (2013.01); A61K 41/0019 (2013.01); A61L 2/007 (2013.01); A61L 2/0029 (2013.01); A61L 2/0035 (2013.01); A61P 1/00 (2018.01); A61L 2202/18 (2013.01); A61L 2202/21 (2013.01);
Abstract

This invention provides a method of sterilizing an S-nitrosothiol, for example S-nitrosoglutathione, without reduction of purity by more than about 5.0% through degradation. The invention allows sterile S-nitrosothiol or a sterile pharmaceutical pre-composition comprising S-nitrosothiol, wherein the S-nitrosothiol is in dry solid form, to be produced. The sterile pharmaceutical pre-composition is mixed with one or more diluents, excipients, carriers, additional active agents, or any combination thereof, for example sterile saline, to prepare a pharmaceutical composition of S-nitrosothiol for use.


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