The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
Jan. 08, 2015
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Genoveffa Franchini, Washington, DC (US);
Rafick-Pierre Sekaly, Port Saint Lucie, FL (US);
Slim Fourati, Cleveland, OH (US);
Mark Cameron, Shaker Heights, OH (US);
Monica Vaccari, Washington, DC (US);
Luca Schifanella, Bethesda, MD (US);
Shari Gordon, Research Triangle Park, NC (US);
Melvin Doster, Beltsville, MD (US);
Namal Malimbada Liyanage, Rockville, MD (US);
The United States of America, as represented by the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Oregon Health & Science University, Portland, OR (US);
Abstract
Compositions including a therapeutically effective amount of an HIV immunogen in combination with an agent that stimulates the Ras pathway, wherein the agent is not an aluminum salt, are disclosed. Methods are also disclosed for inducing an immune response to HIV, and/or to inhibit or treat HIV infection, in a subject, using an HIV immunogen and an agent that stimulates the Ras pathway. Methods also are disclosed for determining if an immunogenic composition will induce a protective response, and/or to determine if an immunogenic composition is of use to prevent or treat an HIV infection. The methods including determining if the immunogenic composition increases the level of one or more components of the Ras signaling pathway.