The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
May. 27, 2015
Applicant:
Ngm Biopharmaceuticals, Inc., South San Francisco, CA (US);
Inventors:
Lei Ling, Foster City, CA (US);
Darrin Anthony Lindhout, Mountain View, CA (US);
Assignee:
NGM Biopharmaceuticals, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/50 (2006.01); A61K 38/00 (2006.01); C12N 15/62 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1825 (2013.01); C07K 14/50 (2013.01); A61K 38/00 (2013.01); C12N 15/62 (2013.01); G01N 2400/00 (2013.01);
Abstract
Provided herein are variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of FGF19 and/or FGF21, and variants or fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.