The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

Oct. 13, 2017
Applicant:

Marshall University Research Corporation, Huntington, WV (US);

Inventors:

Miaozong Wu, Warrensburg, MO (US);

Cuifen Wang, Huntington, WV (US);

Eric Blough, Huntington, WV (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/30 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 9/10 (2006.01);
U.S. Cl.
CPC ...
A61K 33/30 (2013.01); A61K 9/0053 (2013.01); A61K 9/0095 (2013.01); A61K 9/10 (2013.01); A61K 45/06 (2013.01);
Abstract

Compositions and methods for treating striated muscle injury, treating striated muscle atrophy, and/or for promoting striated muscle growth are provided and include administering zinc oxide nanoparticles to a subject in need thereof. The zinc oxide nanoparticles can be adminstered before, during, and/or after exposure to an injurious stimuli, such as radiation. Administration of the zinc oxide nanoparticles reduces activation of autophagy regulators, increases striated muscle anabolism, increases DNA repair signaling, and/or increases striated muscle protein synthesis and growth.


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