The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
Mar. 12, 2014
Applicant:
Stichting Het Nederlands Kanker Instituut-antoni Van Leeuwenhoek Ziekenhuis, Amsterdam, NL;
Inventors:
Chong Sun, Amsterdam, NL;
Rene Bernards, Amsterdam, NL;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); A61K 45/06 (2006.01); A61K 31/4184 (2006.01); A61K 31/5377 (2006.01); A61K 31/166 (2006.01);
U.S. Cl.
CPC ...
A61K 31/517 (2013.01); A61K 31/166 (2013.01); A61K 31/4184 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01);
Abstract
The current disclosure relates to pharmaceutical combinations and compositions useful in the treatment of certain types of cancer. The disclosure also relates to method of treatment these certain types of cancer. In particular, the disclosure relates to the combined use of inhibitors of MEK, EGFR and ERBB2 in the treatment of KRAS-mutant lung cancer, and KRAS-mutant colon cancer.