The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
Jan. 19, 2018
Applicant:
Morvus Technology Ltd, Becon, Powys, GB;
Inventor:
Richard J. Knox, Carmarthen, GB;
Assignee:
MORVUS TECHNOLOGY LIMITED, Brecon, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/396 (2006.01); A61P 17/00 (2006.01); C07D 203/14 (2006.01); C07B 31/00 (2006.01); A61K 31/04 (2006.01); A61K 31/045 (2006.01); A61K 31/12 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); A61M 11/02 (2006.01); A61M 15/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/396 (2013.01); A61K 9/0014 (2013.01); A61K 31/04 (2013.01); A61K 31/045 (2013.01); A61K 31/12 (2013.01); A61K 45/06 (2013.01); A61M 11/02 (2013.01); A61M 15/009 (2013.01); C07B 31/00 (2013.01); C07D 203/14 (2013.01); A61M 2202/064 (2013.01);
Abstract
There is provided the use as reducing agents of alpha-hydroxycarbonyl compounds capable of forming cyclic dimers. There is also provided corresponding methods of reducing reducible compounds, particularly reduction-activated prodrugs. Examples of the alpha-hydroxycarbonyl compounds used are dihydroxyacetone, glycolaldehyde, glyceraldehyde, erythrose, xylulose, erythrulose or 3-hydroxy-2-butanone.