The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2019

Filed:

May. 05, 2016
Applicants:

Temple University of the Commonwealth System of Higher Education, Philadelphia, PA (US);

Villanova University, Villanova, PA (US);

Inventors:

William Wuest, Wallingford, PA (US);

Kevin Patrick Minbiole, Media, PA (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 33/12 (2006.01); A01N 33/04 (2006.01); C07C 211/63 (2006.01); C07C 323/25 (2006.01); A01N 43/40 (2006.01); C07D 213/22 (2006.01);
U.S. Cl.
CPC ...
A01N 33/12 (2013.01); A01N 43/40 (2013.01); C07C 211/63 (2013.01); C07C 323/25 (2013.01); C07D 213/22 (2013.01);
Abstract

The present disclosure provides an antimicrobial composition including a polycationic amphiphile compound, and the method of making and the method of using such a compound or composition. The compound having the formula R, R, R, R, R, R, R, or Ris H or a Calkyl unsubstituted or optionally substituted with a functional group such as —OH, —OR', —NH, —NHR′, —NR′, —N—C(O)R′, —N—C(O)CR′═CR′, —SH, —SR′, —O—C(O)R′, —C(O)R′, —CF, —OCF, halogen, benzyl, o-vinylbenzyl, m-vinylbenzyl, p-vinylbenzyl, phenyl, allyl, and substituted allyl. R, Ror Ris a Calkyl unsubstituted or optionally substituted with a functional group such as —OH, —OR′, —NH, —NHR′, —SH, —SR′, —O—C(O)R′, —C(O)R′, —CF, and —OCF. R′ is H or a Calkyl. X or Y is a halogen. m and n are integers in the range from 1 to 25.


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