The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2019
Filed:
Dec. 28, 2011
Masakazu Hashimoto, Suita, JP;
Hiroyuki Nakagawa, Osaka, JP;
Mikio Aoki, Osaka, JP;
Lars O. Tjernberg, Huddinge, SE;
Bengt Winblad, Huddinge, SE;
Masakazu Hashimoto, Suita, JP;
Hiroyuki Nakagawa, Osaka, JP;
Mikio Aoki, Osaka, JP;
Lars O. Tjernberg, Huddinge, SE;
Bengt Winblad, Huddinge, SE;
DAINIPPON SUMITOMO PHARMA CO., LTD., Osaka, JP;
Abstract
The present invention provides an agent for determining Alzheimer's disease, comprising an anti-S38AA antibody, a method of determining Alzheimer's disease in a test animal, comprising detecting an S38AA fragment in a sample collected from said animal, and a method of screening for a substance that treats or prevents Alzheimer's disease, comprising contacting a test substance with a cell permitting measurement of production of a S38AA fragment, measuring the production amount of the S38AA fragment in the cell, and comparing the production amount with that of the S38AA fragment in a control cell free of contact with the test substance, and selecting a test substance that down-regulates the production amount of the S38AA fragment as a substance capable of treating or preventing Alzheimer's disease, based on the comparison results.