The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2019

Filed:

Nov. 01, 2017
Applicant:

Critical Care Diagnostics, Inc., San Diego, CA (US);

Inventor:

James V. Snider, San Diego, CA (US);

Assignee:

Critical Care Diagnostics, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/68 (2006.01); A61P 9/00 (2006.01); C07K 14/47 (2006.01); C07K 14/715 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); G01N 33/53 (2013.01); G01N 33/68 (2013.01); G01N 33/6869 (2013.01); C07K 14/47 (2013.01); C07K 14/4726 (2013.01); C07K 14/715 (2013.01); G01N 2333/4724 (2013.01); G01N 2333/7155 (2013.01); G01N 2800/32 (2013.01); G01N 2800/325 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01); G01N 2800/54 (2013.01); G01N 2800/56 (2013.01);
Abstract

Provided are methods for evaluating the risk of an adverse clinical outcome in a subject, deciding whether to discharge or continue treating a subject (e.g., treatment on an inpatient basis), or to initiate or terminate treatment, selecting a subject for participation in a clinical study, and selecting a therapeutic treatment for a subject that include determining a level of ST2 in a biological sample from the subject and determining a level of galectin-3 in a biological sample from the subject. Kits are also provided that contain an antibody that specifically binds to ST2, an antibody that specifically binds to galectin-3, and instructions for using the kit to evaluate the risk of an adverse clinical outcome in a subject, to decide whether to discharge or continue treating a subject (e.g., treatment on an inpatient basis) or to initiate or terminate treatment, to select a subject for participation in a clinical study, and/or to select treatment for a subject.


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