The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2019
Filed:
Nov. 23, 2015
Applicant:
Gentium S.r.l., Villa Guardia (CO), IT;
Inventors:
Terenzio Ignoni, San Fermo Della Battaglia, IT;
Vijay Kumar, Casnate, IT;
Claudio Verga, Bregnano, IT;
Assignee:
GENTIUM S.R.L., Villa Guardia (CO), IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5014 (2013.01); G01N 33/5064 (2013.01);
Abstract
The present invention relates to cell-based methods for determining the biological activity of defibrotide. In particular, the invention provides a method for assessing the potency of defibrotide by assessing the viability of mammalian cells in the presence of at least one cytotoxic agent and one or more concentrations of defibrotide. Such methods are particularly useful for standardizing pharmaceutical compositions comprising defibrotide.