The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2019
Filed:
Oct. 17, 2013
University of Maryland, Office of Technology Commercialization, College Park, MD (US);
Children's National Medical Center, Washington, DC (US);
The United States of America, As Represented BY the Secretary, Department of Health and Human, Washington, DC (US);
Omar Bilal Ayyub, Potomac, MD (US);
Adam Michael Behrens, Olney, MD (US);
Peter Kofinas, Bethesda, MD (US);
Marshall Lynn Summar, Washington, DC (US);
Juan Manuel Cabrera-Luque, Rockville, MD (US);
Gary Cunningham, Washington, DC (US);
Anton Simeonov, Bethesda, MD (US);
Juan Marugan, Gaithersburg, MD (US);
University of Maryland, College Park, College Park, MD (US);
Children's National Medical Center, Washington, DC (US);
The United States of America, as Represented by The Secretary, Department of Health and Human Services, Bathesda, MD (US);
Abstract
The present invention relates to a biosensor capable of measuring the total concentration of one or a plurality of amino acids with the use of a reagentless system comprising an electrode modified by hydrogel that comprises at least one enzyme that oxidizes at least one substrate that is at least one amino acid. In some embodiments, the biosensor comprises a hydrogel comprising alginate. In some embodiments, the biosensor comprises use of a thermophilic bacterial metabolic enzyme immobilized or attached to the hydrogel.