The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2019
Filed:
Jan. 06, 2015
Hadasit Medical Research Services and Development Ltd., Jerusalem, IL;
Hilla Giladi, Mevaseret Zion, IL;
Alina Simerzin, Jerusalem, IL;
Yael Hantz, Jerusalem, IL;
Sagit Arbel Alon, Reut, IL;
Eithan Galun, Har-Adar, IL;
HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD., Jerusalem, IL;
Abstract
The present invention provides miR-122* as a functional microRNA molecule, compositions comprising the same and uses thereof for treatment of various conditions, such as, cancer. Further provided are methods for increasing the expression, stability and/or activity of p53 in a target cell or method for inducing cancer cell death, the methods comprising introducing into the cell a miR-122* polynucleotide molecule or a vector expressing or encoding the same.