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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10392608 B1

PDFFull Text
Date of Patent:
Aug. 27, 2019

Filed:

Feb. 27, 2018

Dimeric bacteriophage lysins

Applicant:

The Rockefeller University, New York, NY (US);

Inventors:

Vincent A. Fischetti, West Hempstead, NY (US);

Gregory Resch, Evian les bains, FR;

Assignee:

The Rockefeller University, New York, NY (US);

Attorney:

Hoffmann & Baron, LLP

Primary Examiner:

Ganapathirama Raghu

Int. Cl.
CPC ...
C12N 9/36 (2006.01); C12N 9/24 (2006.01); A61K 38/47 (2006.01); A01N 63/02 (2006.01); C12N 7/02 (2006.01); C12N 9/80 (2006.01); A01N 63/00 (2006.01); C07K 14/005 (2006.01); A61K 38/00 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2462 (2013.01); A01N 63/00 (2013.01); A01N 63/02 (2013.01); A61K 38/47 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); C12N 9/2405 (2013.01); C12N 9/80 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C12N 2795/10022 (2013.01); C12N 2795/10033 (2013.01); C12N 2795/10071 (2013.01); C12Y 302/01017 (2013.01);
Abstract

The present invention provides isolated dimeric-specific phage lysins having two-specific phage lysin monomers covalently linked to each other, and having killing activity against one or morebacteria. Also provided for are pharmaceutical compositions of dimeric lysins and their use in therapeutic treatment or alleviation of infections or bacterial colonizations. The dimeric lysins may also be used to decontaminate porous and non-porous surfaces or devices.

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Fischetti, Vincent. (2019). Dimeric bacteriophage lysins (U.S. Patent No. 10392608). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10392608

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