The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2019
Filed:
Aug. 28, 2014
Glaxosmithkline Biologicals S.a., Rixensart, BE;
The Chemo-sero-therapeutic Research Institute, Kumamoto, JP;
Pascal Charles Louis Gerkens, Rixensart, BE;
Michele Therese Rita Lecocq, Rixensart, BE;
Tatsuya Kasugaya, Kumamoto, JP;
Kenjiro Kawatsu, Kumamoto, JP;
Yoshinobu Miyatsu, Kumamoto, JP;
Tetsuro Tanabe, Kumamoto, JP;
The Chemo-Sero-Therapeutic Research Institute, Kumamoto, JP;
Abstract
A method of producing a virus in cell culture comprising at least the steps of a) providing a population of cells cultured in a cell culture medium, b) infecting the population of cells by i. inoculating the population with the virus, and ii. incubating the inoculated population so as to allow the virus to replicate and propagate, c) collecting the produced virus, thereby providing a viral harvest, and d) purifying the virus, wherein a power density of at least 15 W/m, at least 30 W/m, at least 60 W/m, at least 100 W/m, at least 120 W/mis applied to the cell culture at least during step b).