The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2019

Filed:

Jul. 06, 2016
Applicant:

Advanced Solutions Life Sciences, Llc, Louisville, KY (US);

Inventors:

Michael W. Golway, Louisville, KY (US);

James B. Hoying, Louisville, KY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 3/06 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12M 29/10 (2013.01); C12M 23/16 (2013.01); C12M 25/14 (2013.01); G01N 33/502 (2013.01); G01N 33/5064 (2013.01);
Abstract

A bona fide adaptable in vitro microcirculation model is provided by integrating a 3-D printed network of endothelial-cell lined perfusion channels, formed via sacrificial casting in a gel matrix, with a native, adaptable microvasculature matured from native microvessels added to the gel matrix. Responsive vascular adaptation exhibited by the in vitro microcirculation is physiologically relevant. Methods for fabricating, devices, models and investigative platforms for pharmaceutical applications, vascular mechanism and microvessel-parenchyma interaction studies, and vascularizing strategies for tissue engineering applications are also disclosed.


Find Patent Forward Citations

Golway, Michael. (2019). Vascularized in vitro perfusion devices, methods of fabricating, and applications thereof (U.S. Patent No. 10392595). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10392595

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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