The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2019
Filed:
May. 13, 2015
Pfizer Inc., New York, NY (US);
Eric M. Bennett, Arlington, MA (US);
Nathan Higginson-Scott, Boston, MA (US);
Lioudmila Tchistiakova, Stoneham, MA (US);
Kimberly A. Marquette, Somerville, MA (US);
Janet E. Paulsen, Londonderry, NH (US);
Ruth E. Gimeno, Carmel, IN (US);
PFIZER INC., New York, NY (US);
Abstract
The present invention relates to engineered heteromultimeric proteins, and more specifically, to methods for producing and purifying heterodimeric proteins, such as bispecific antibodies and. Methods for producing and purifying such engineered heterodimeric proteins and their use in diagnostics and therapeutics are also provided. The present invention also relates to a humanized antibody that specifically binds human TrkB and methods for producing and using the antibody to, inter alia, treat a hearing loss disorder.