The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2019

Filed:

Dec. 06, 2017
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Huda Akil, Ann Arbor, MI (US);

Stanley Watson, Ann Arbor, MI (US);

Cortney Turner, Willis, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 39/00 (2006.01); A61P 25/24 (2006.01); A61P 25/22 (2006.01); C07K 16/22 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 38/18 (2013.01); A61P 25/22 (2018.01); A61P 25/24 (2018.01); G01N 33/50 (2013.01); G01N 33/6893 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/76 (2013.01); G01N 2333/475 (2013.01); G01N 2500/04 (2013.01); G01N 2800/30 (2013.01); G01N 2800/301 (2013.01); G01N 2800/304 (2013.01);
Abstract

The methods of the present invention are useful for determining whether an individual has or is at risk of developing an affective disorder by detecting the expression level of connective tissue growth factor (CTGF) in a biological sample. The methods of the present invention are also useful for identifying compounds that modulate (e.g., decrease) the expression level or activity of CTGF. The present invention further provides therapeutic methods that target CTGF for the treatment of an affective disorder.


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