The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2019
Filed:
Oct. 30, 2017
Applicant:
Apicore Us Llc, Somerset, NJ (US);
Inventors:
Ravishanker Kovi, Monroe, NJ (US);
Jayaraman Kannapan, Gujarat, IN;
Ananda Babu Thirunavakarasu, Gujarat, IN;
Piyush D. Fadadu, Gujarat, IN;
Piyush B. Thumar, Gujarat, IN;
Assignee:
Apicore US LLC, Somerset, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/16 (2006.01);
U.S. Cl.
CPC ...
C07H 19/16 (2013.01); C07B 2200/13 (2013.01);
Abstract
Processes are provided for the preparation of a stable polymorphic form C of regadenoson, the process involving steps of a) obtaining a solution of regadenoson in benzyl alcohol solvent, b) maintaining the reaction mixture of step a) to about 10° C. to about 90° C., and c) isolating the stable polymorphic form C of regadenoson. Polymorphic form C may be characterized by an x-ray powder diffraction pattern with peaks at about 6.1, 10.2, 10.6, 19.0 and 25.4.±0.2 degrees 2-theta.