The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2019
Filed:
Jul. 31, 2018
Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);
Erik Fenster, San Bruno, CA (US);
Tom M. Lam, San Francisco, CA (US);
Mandy Loo, San Jose, CA (US);
Robert Murray McKinnell, Millbrae, CA (US);
Anthony Francesco Palermo, San Francisco, CA (US);
Diana Jin Wang, Dublin, CA (US);
Breena Fraga, Madera, CA (US);
Jerry Nzerem, South San Francisco, CA (US);
Marta Dabros, Foster City, CA (US);
Venkat R. Thalladi, Foster City, CA (US);
Miroslav Rapta, San Carlos, CA (US);
THERAVANCE BIOPHARMA R&D IP, LLC, South San Francisco, CA (US);
Abstract
The invention provides compounds of formula (I): or a pharmaceutically-acceptable salt thereof, wherein the variables are defined in the specification, that are inhibitors of JAK kinases, particularly JAK3. The invention also provides crystalline forms, pharmaceutical compositions comprising such compounds, methods of using such compounds to treat gastrointestinal and other inflammatory diseases, and processes and intermediates useful for preparing such compounds.