The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2019
Filed:
Apr. 21, 2017
Applicant:
The Cleveland Clinic Foundation, Cleveland, OH (US);
Inventor:
Mohamed Abazeed, Cleveland, OH (US);
Assignee:
THE CLEVELAND CLINIC FOUNDATION, Cleveland, OH (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2006.01); A61N 5/10 (2006.01); A61K 51/00 (2006.01); A61K 31/545 (2006.01); A61K 45/06 (2006.01); A61K 31/167 (2006.01); A61K 31/277 (2006.01); A61K 31/402 (2006.01); A61K 31/4164 (2006.01); A61K 31/4166 (2006.01); A61K 31/496 (2006.01); A61K 31/57 (2006.01); A61K 31/585 (2006.01); A61N 5/00 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0038 (2013.01); A61K 31/167 (2013.01); A61K 31/277 (2013.01); A61K 31/402 (2013.01); A61K 31/4164 (2013.01); A61K 31/4166 (2013.01); A61K 31/496 (2013.01); A61K 31/545 (2013.01); A61K 31/57 (2013.01); A61K 31/585 (2013.01); A61K 41/0019 (2013.01); A61K 45/06 (2013.01); A61K 51/00 (2013.01); A61N 5/00 (2013.01); A61N 5/10 (2013.01); A61N 2005/1098 (2013.01);
Abstract
Provided herein are compositions, systems, kits, and methods for treating cancer in a subject with androgen receptor positive cancer cells by sensitizing such cancer cells with anti-androgen receptor therapy (e.g., Enzalutamide or anti-androgen antibody), and then treating with radiation therapy.