The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2019

Filed:

Jul. 12, 2013
Applicant:

Commissariat a L'energie Atomique ET Aux Energies Alternatives, Paris, FR;

Inventors:

Tristan Petit, Paris, FR;

Jean-Charles Arnault, Rambouillet, FR;

Hugues Girard, Viroflay, FR;

Romain Grall, Fontenay aux Roses, FR;

Sylvie Chevillard, Paris, FR;

Jozo Delic, Bourg la Reine, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C01B 32/25 (2017.01); A61K 41/00 (2006.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01); B82Y 5/00 (2011.01); A61K 31/713 (2006.01); A61N 5/06 (2006.01); A61N 5/10 (2006.01); C12N 15/113 (2010.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 41/0038 (2013.01); A61K 9/0009 (2013.01); A61K 9/5115 (2013.01); A61K 31/713 (2013.01); A61K 47/6921 (2017.08); A61N 5/062 (2013.01); A61N 5/10 (2013.01); B82Y 5/00 (2013.01); C01B 32/25 (2017.08); C12N 15/1137 (2013.01); A61N 2005/0661 (2013.01); A61N 2005/1087 (2013.01); A61N 2005/1091 (2013.01); C12N 2310/14 (2013.01); C12N 2310/351 (2013.01); C12N 2320/30 (2013.01); Y10T 428/2982 (2015.01);
Abstract

The present invention relates to the use of nanodiamonds as drugs generating free radicals, in particular for treating tumors. The invention is based on generating free radicals on the surface of the nanodiamonds when they are exposed to radiation, for example ionizing radiation. In order to increase the effectiveness of the nanodiamonds, the nanodiamonds can be complexed with a radiosensitizing agent, such as a chemical molecule or an interfering RNA targeting a repairing gene.


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