The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2019

Filed:

Aug. 12, 2016
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

Children's Medical Center Corporation, Boston, MA (US);

Inventors:

George Cheeran Verghese, Newton, MA (US);

Margaret Gan Guo, San Diego, CA (US);

Rebecca Mieloszyk, Redmond, WA (US);

Thomas Heldt, Cambridge, MA (US);

Baruch Shlomo Krauss, Brookline, MA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/083 (2006.01); G16C 20/30 (2019.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
G16C 20/30 (2019.02); A61B 5/0836 (2013.01); A61B 5/4821 (2013.01); A61B 5/7264 (2013.01); A61B 5/7271 (2013.01); A61B 5/746 (2013.01);
Abstract

Systems and methods are disclosed herein for quantitatively identifying a patient's sedation level and predicting adverse events, based on one or more capnograms or outputs from a pharmacokinetic, pharmacodynamic, or ventilatory model. A sensor measures a carbon dioxide concentration of air exhaled by a patient into a breath receiver. A processor processes the sensor data to generate a capnogram including one or more respiratory cycles, computes the outputs of pharmacokinetic, pharmacodynamic, or ventilatory models, and extracts one or more of the resulting features from the capnogram and pharmacokinetic, pharmacodynamic, or ventilatory model outputs. A multi-parameter metric is computed based on the one or more extracted features and estimates the current or predicted sedation level of the patient.


Find Patent Forward Citations

Loading…