The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2019

Filed:

Jun. 27, 2017
Applicants:

Ventana Medical Systems, Inc., Tucson, AZ (US);

Hoffmann-la Roche, Inc., Little Falls, NJ (US);

Inventors:

Quan Yuan, San Jose, CA (US);

Srinivas Chukka, San Jose, CA (US);

Gerardo Fernandez, Chappaqua, NY (US);

Elizabeth Little, San Jose, CA (US);

Angelika Fuchs, Munich, DE;

Assignees:

Ventana Medical Systems, Inc., Tucson, AZ (US);

Hoffmann-La Roche, Inc., Little Falls, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G06T 7/00 (2017.01);
U.S. Cl.
CPC ...
G06T 7/0012 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/20168 (2013.01); G06T 2207/30101 (2013.01);
Abstract

Systems and methods for analyzing vessels in multiplexed images include detecting large vessels using a spoke feature detection method, detecting long and narrow vessels using a line feature detection method, detecting smaller vessels using rolling-ball filtering and binary image operations to generate a mask, and evaluating any contour polygons resulting from these operations using quality measurements and other thresholds. Maturity determination and nuclei detection are also performed, resulting in an output of vessel characteristics and co-locations enabling enhanced analysis of multispectral images.


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