The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2019

Filed:

Dec. 22, 2016
Applicants:

Canon U.s. Life Sciences, Inc., Rockville, MD (US);

University of Maryland, College Park, College Park, MD (US);

Inventors:

Giuliano Scarcelli, Washington, DC (US);

Jitao Zhang, College Park, MD (US);

Antonio Fiore, Hyattsville, MD (US);

Hanyoup Kim, Rockville, MD (US);

Assignees:

Canon U.S. Life Sciences, Inc., Rockville, MD (US);

University of Maryland, College Park, College Park, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/00 (2006.01); G01N 15/14 (2006.01); G01N 15/00 (2006.01); G01N 21/63 (2006.01);
U.S. Cl.
CPC ...
G01N 15/1434 (2013.01); G01N 2015/0065 (2013.01); G01N 2015/1495 (2013.01); G01N 2021/638 (2013.01);
Abstract

The present invention relates to a method and system for a label-free cell analysis based on Brillouin light scattering techniques. Combined with microfluidic technologies according to the present invention, Brillouin spectroscopy constitutes a powerful tool to analyze physical properties of cells in a contactless non-disturbing manner. Specifically, subcellular mechanical information can be obtained by analyzing the Brillouin spectrum of a cell. Furthermore, a novel configuration of Brillouin spectroscopy is provided to enable simultaneous analysis of multiple points in a cell sample.


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